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JIP-3 Polyclonal Antibody, 100ul Enzymes alternatively spliced transcript variants encoding

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JIP-3 Polyclonal Antibody, 100ul Enzymes alternatively spliced transcript variants encodingC Jun amino terminal kinase interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart

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Description

alternatively spliced transcript variants encoding a range of isoforms have been described

which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation

Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia

resulting in non-apoptotic cell death of dopaminergic nerve cells

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A

JIP-3 Polyclonal Antibody, 100ul Enzymes alternatively spliced transcript variants encodingC Jun amino terminal kinase interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart

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