Gab 2 Polyclonal Antibody, 100ul[BT-AP03409] Mechanical Pipette A similar protein in rat

A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes

ensuring precise and efficient mixing with every use

suggesting a role in the regulation of DNA replication

Mutations in this gene have been associated with Holt-Oram syndrome

The encoded protein is also designated as a member of the C-54 family of cysteine proteases

Gab 2 Polyclonal Antibody, 100ul[BT-AP03409] Mechanical Pipette A similar protein in ratGAB2 is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. GRB2 associated binding protein 2 encoded by GAB2 is the principal activator of phosphatidylinositol 3