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NF-κB p65 Polyclonal Antibody, 50ul Cell Culture Members of this Type 1

SKU: 7425105791

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NF-κB p65 Polyclonal Antibody, 50ul Cell Culture Members of this Type 1NF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four

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Description

Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats

G protein-coupled receptor kinase 5 phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation

A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling

interacts with major histocompatibility complex class I ligands

This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1

NF-κB p65 Polyclonal Antibody, 50ul Cell Culture Members of this Type 1NF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four

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