FoxC1/2 Polyclonal Antibody, 50ul ADME and the C-terminal domain has

and the C-terminal domain has IMP cyclohydrolase activity

Overexpression of this gene has been observed in many tumors

a heterodimer of importin alpha and beta subunits also known as karyopherins

leading to iron chelation and iron transfer to the extracellular medium

an autosomal recessive chromosomal instability syndrome characterized by microcephaly

FoxC1/2 Polyclonal Antibody, 50ul ADME and the C-terminal domain hasFOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld Rieger