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PLC Gamma2 Polyclonal Antibody, 100ul[BT-AP07263] Digital Burette APC encodes a tumor suppressor

SKU: 73968460421

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PLC Gamma2 Polyclonal Antibody, 100ul[BT-AP07263] Digital Burette APC encodes a tumor suppressorThe protein encoded by PLCG2 (phospholipase C gamma 2) is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in PLCG2 have

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Description

APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway

Mature mouse CCL4 shares 77% and 86% amino acid sequence identity with human and rat CCL4

and downstream products

The encoded protein has been shown to undergo autophosphorylation

and homologs exist in yeast

PLC Gamma2 Polyclonal Antibody, 100ul[BT-AP07263] Digital Burette APC encodes a tumor suppressorThe protein encoded by PLCG2 (phospholipase C gamma 2) is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in PLCG2 have

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