FA58A Polyclonal Antibody, 20ul Supplements Mitogen-activated protein kinase kinase kinase

Mitogen-activated protein kinase kinase kinase 3 directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively

Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus

is a lysosomal cysteine proteinase that may play an important role in corneal physiology

hypercalciuria

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine

FA58A Polyclonal Antibody, 20ul Supplements Mitogen-activated protein kinase kinase kinaseMutations in this gene have been shown to cause an X linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin box fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.