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Subchondral bone disease is not technically a disease but rather the result of micro-injuries to the subchondral and trabecular bone

The driver may be mast-cell-mediated or systemic rather than NF-B-local, and if so, increasing the dose for additional KPV will not address it see the mast-cell note under Phenotype Considerations

Thyroid dysfunction requires lab testing to confirm and treat

Inflammation and micro-tears in these tendons rank among the most common causes of shoulder pain, especially after age 40

Individual results vary enormously based on injury severity, overall health, compliance with rehabilitation, and other factors

Overview Diagnostic imaging and laboratory testing are critical to determining a patient's course of treatment