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p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials The protein encoded by this

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p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials The protein encoded by thisThe protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

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Description

The protein encoded by this intronless gene is found in the nucleus| where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis

This gene is expressed early during development| and its expression has been detected in lung and meningioma tumors

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It has been also shown to play an important role in the proliferation and differentiation of B cells

and is a receptor for C-C type chemokines

p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials The protein encoded by thisThe protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

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