GFR Alpha-4 Polyclonal Antibody, 50ul Immunology The protein encoded by PTPRC

The protein encoded by PTPRC (protein tyrosine phosphatase

000 live births

Defects in this gene are associated with isolated cleft palate and mental retardation

and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation

These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins

GFR Alpha-4 Polyclonal Antibody, 50ul Immunology The protein encoded by PTPRCThe protein encoded by GFRA4 (GDNF family receptor alpha 4)is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. GFRA4 is a candidate gene for RET associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4.