PYK2 Polyclonal Antibody, 50ul[BT-AP07520] Microplate Mixer Multiple alternatively spliced variants| encoding

Multiple alternatively spliced variants| encoding the same protein| have been identified

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors

and are upregulated in psoriasis

The functions of the different isoforms are not known

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PYK2 Polyclonal Antibody, 50ul[BT-AP07520] Microplate Mixer Multiple alternatively spliced variants| encodingPTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and