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EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 50ul Liquid Handling &Storage Let's do this

SKU: 72676815

4.7
USD185.00 USD218.00

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EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 50ul Liquid Handling &Storage Let's do thisThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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Description

Let's do this

|tissue specificity:Leukemic stem cell

A recent study showed this gene to be an authentic stop codon readthrough target| and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon

contains N-acetylglucosamine| probably O-linked

a subset of the larger NUDIX hydrolase family

EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 50ul Liquid Handling &Storage Let's do thisThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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