Bag-3 Polyclonal Antibody, 20ul[BT-AP00818] Monoclonal Antibodies A dominant negative mutant of

A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer

Maximum operating temperature: 45ºC

is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues

copper- and zinc- binding domains at the N-terminus

No autofluorescence

Bag-3 Polyclonal Antibody, 20ul[BT-AP00818] Monoclonal Antibodies A dominant negative mutant ofBAG proteins compete with Hip for binding to the Hsc70 Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45 amino acid BAG domain near the C terminus but differ markedly in their N terminal regions. The protein encoded by BAG3 (BCL2 associated athanogene 3) contains a WW domain in the N terminal region and a BAG domain in the C terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically