PDK2 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Noonan syndrome and trisomy 12p

Noonan syndrome and trisomy 12p

septic shock

which causes progressive bone overgrowth

Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner

a protein involved in the nucleotide excision repair (NER)

PDK2 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Noonan syndrome and trisomy 12pPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.