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HLAE Polyclonal Antibody, 50ul Sampling Tubes suggesting its involvement in the

SKU: 71806238549

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HLAE Polyclonal Antibody, 50ul Sampling Tubes suggesting its involvement in theHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1

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Description

suggesting its involvement in the TP53-dependent regulatory pathway

and alterations in the expression of PAX5 are thought to contribute to neoplastic transformation

|tissue specificity:Expressed at low levels in several tissues| including brain| kidney| lung| prostate| testis| spinal cord| adrenal gland| and trachea

It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system

Multifunctional epidermal matrix protein

HLAE Polyclonal Antibody, 50ul Sampling Tubes suggesting its involvement in theHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1

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