DSCR 1 Polyclonal Antibody, 100ul Enzymes Members of this family function

Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water

the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8

A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13

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The CARL-1 monoclonal antibody reacts with human TWEAK

DSCR 1 Polyclonal Antibody, 100ul Enzymes Members of this family functionRegulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.