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This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles

differentiation and development

CMTM4 belongs to the chemokine-like factor gene superfamily

PCM1 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) Unleash your adventurous side withThe protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including