Karyopherin Alpha2 Polyclonal Antibody, 100ul Gene Editing form a cytokine receptor gene

form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

Functional analysis showed that this gene product has both ATPase and DNA helicase activities

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors

The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP

lipid rafts

Karyopherin Alpha2 Polyclonal Antibody, 100ul Gene Editing form a cytokine receptor geneThe import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy independent docking of the protein to the nuclear envelope and the second is an energy dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in