Caspase-8 Polyclonal Antibody, 20ul[BT-AP07124] Plasmid Preparation an autosomal recessive disease associated

an autosomal recessive disease associated with a susceptibility to pyogenic infections

and the truncated form additionally interacts with CCR1 and CCR2

An important paralog of this gene is BARX2

where it binds OGF and is translocated into the nucleus

the encoded protein binds to the putative leucine zipper domain of macroH2A1

Caspase-8 Polyclonal Antibody, 20ul[BT-AP07124] Plasmid Preparation an autosomal recessive disease associatedThis gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large