PLCB1 Polyclonal Antibody, 100ul Centrifugal Filter with both 4-hydroxylation and 18-hydroxylation

with both 4-hydroxylation and 18-hydroxylation activities

Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization

suggesting a role in the regulation of DNA replication

The members of this family share structural similarity

Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder

PLCB1 Polyclonal Antibody, 100ul Centrifugal Filter with both 4-hydroxylation and 18-hydroxylationThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G protein alpha subunits, alpha q and alpha 11. Two transcript variants encoding different isoforms have been found for this gene.