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SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The activity of eukaryotic elongation

SKU: 6990029809

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SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The activity of eukaryotic elongationThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

The activity of eukaryotic elongation factor 2 kinase is increased in many cancers and may be a valid target for anti-cancer treatment

Studies in other mammals suggest this protein plays a role in cell adhesion

CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction

which is several orders of magnitude faster than conventional molecular motor proteins

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The activity of eukaryotic elongationThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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