Tau (Acetyl Lys686) Polyclonal Antibody, 20ul Thermal Control Mutations and deletions in NKX2-1

Mutations and deletions in NKX2-1 are associated with benign hereditary chorea

It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6)

This proto-oncogene may play a role in the regulation of embryonic development and cell growth

This protein is involved in cell adhesion

Translocations between this gene and many other partner genes have been observed in different leukemias

Tau (Acetyl Lys686) Polyclonal Antibody, 20ul Thermal Control Mutations and deletions in NKX2-1This gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,