Gab 1(Phospho Tyr627) Polyclonal Antibody, 50ul Cell Screening and Imaging including hereditary cancers such as

including hereditary cancers such as Li-Fraumeni syndrome

Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity

The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1

May be required for pre-mRNA splicing

It phosphorylates the eukaryotic initiation factor 4E (eIF4E)

Gab 1(Phospho Tyr627) Polyclonal Antibody, 50ul Cell Screening and Imaging including hereditary cancers such asThe protein encoded by this gene is a member of the IRS1 like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.