SLAP1 Polyclonal Antibody, 50ul Serological Pipets This gene encodes a member

This gene encodes a member of the 5'-3' exonuclease family

Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia

The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members

VDAC1 encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane

Two alternative transcript variants encoding different protein isoforms have been described for this gene

SLAP1 Polyclonal Antibody, 50ul Serological Pipets This gene encodes a memberThe C terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization.,Adapter protein, which negatively regulates T cell receptor (TCR) signaling. Inhibits T cell antigen receptor induced activation of nuclear factor of activated T cells. Involved in the negative