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IKK Epsilon(Phospho-Ser172) Rabbit Polyclonal Antibody, 50ul Funnels and cleft lip/palate syndrome 3

SKU: 6857837912

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IKK Epsilon(Phospho-Ser172) Rabbit Polyclonal Antibody, 50ul Funnels and cleft lip/palate syndrome 3IKBKE is a noncanonical I kappa B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al. 2009

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Description

and cleft lip/palate syndrome 3 (EEC3)| split-hand/foot malformation 4 (SHFM4)| ankyloblepharon-ectodermal defects-cleft lip/palate| ADULT syndrome (acro-dermato-ungual-lacrim

a leukocyte-specific adaptor protein important for immune cell signaling

differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence

This gene product is the human homolog of mouse Tbx2

|PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity

IKK Epsilon(Phospho-Ser172) Rabbit Polyclonal Antibody, 50ul Funnels and cleft lip/palate syndrome 3IKBKE is a noncanonical I kappa B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al. 2009

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