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ARK-1 Polyclonal Antibody, 100ul[BT-AP00610] Peptide Modification C8 is one component of

SKU: 68201271496

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ARK-1 Polyclonal Antibody, 100ul[BT-AP00610] Peptide Modification C8 is one component ofThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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Description

C8 is one component of the membrane attack complex

a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells

T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss

but it is more likely that this component is a different but very similar protein

Loss of function or expression of this gene is associated with decreased apoptosis

ARK-1 Polyclonal Antibody, 100ul[BT-AP00610] Peptide Modification C8 is one component ofThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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