HMGN1/2/3/4 Rabbit Polyclonal Antibody, 100ul Cell Proliferation The encoded protein undergoes an

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired

including those leading to cell proliferation

The protein encoded by PRF1 (perforin 1) has structural and functional similarities to complement component 9 (C9)

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

Mitogen-activated protein kinase kinase kinase MLT

HMGN1/2/3/4 Rabbit Polyclonal Antibody, 100ul Cell Proliferation The encoded protein undergoes anThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMG17 the encoded protein may help maintain an open chromatin configuration around transcribable genes.