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STXB2 Rabbit Polyclonal Antibody, 50ul Stepper This protein was first identified

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STXB2 Rabbit Polyclonal Antibody, 50ul Stepper This protein was first identifiedThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells| however

The calcium channel consists of a complex of alpha-1| alpha-2/delta| beta| and gamma subunits in a 1:1:1:1 ratio

Activates RAC1

The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine

PTGIS (prostaglandin I2 (prostacyclin) synthase) encodes a member of the cytochrome P450 superfamily of enzymes

STXB2 Rabbit Polyclonal Antibody, 50ul Stepper This protein was first identifiedThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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