DUS2L Polyclonal Antibody, 50ul DNA Synthesis PTM:Phosphorylated by GSK3B

PTM:Phosphorylated by GSK3B

Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN)

PTM:Phosphorylated on tyrosines by FYN (By similarity)

Belongs to the IFRD family

This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp)

DUS2L Polyclonal Antibody, 50ul DNA Synthesis PTM:Phosphorylated by GSK3BDUS2 (dihydrouridine synthase 2) encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon induced protein kinase. DUS2 has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described