ASPP1 Polyclonal Antibody, 20ul Peptide Synthesis where it activates Ras

where it activates Ras

It binds mutliple lipid-containing molecules| including phosphatidylserine| phosphatidylinositol 4-phosphate (PI4P) and oxysterol| and promotes their exchange between the endoplasmic reticulum and the plasma membrane

disease:A chromosomal aberration involving FOXO4 is found in acute leukemias

trichohyalin

Alternativley spliced transcript variants encoding different isoforms have been identified in this gene

ASPP1 Polyclonal Antibody, 20ul Peptide Synthesis where it activates RasThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F