AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases Histones play a critical role

Histones play a critical role in transcriptional regulation

This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2

MAP kinases act as an integration point for multiple biochemical signals

This gene product is a key molecule in ion channel regulation and synaptic exocytosis

Two related pseudogenes have been identified on chromosome 16

AS160(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases Histones play a critical roleThis gene is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by this gene is a Rab GTPase activating protein and contains two phopshotyrosine binding domains (PTB1 and PTB2) a calmodulin binding domain (CBD) a Rab GTPase domain and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter 4 (GLUT4) important for