PTGR2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes The gene was first identified

The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site

The alleles of this gene exhibit an unusual amount of sequence variation| such that the alleles were once thought to represent two separate gene

Two related pseudogene have been identified on chromosomes 20 and X

ubiquitination targets the protein for rapid degradation via the ubiquitin system

Polymorphisms in this gene may be associated with osteoarthritis in human patients

PTGR2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes The gene was first identifiedPTGR2 encodes an enzyme involved in the metabolism of prostaglandins. Prostaglandin reductase 2 catalyzes the NADPH dependent conversion of 15 keto prostaglandin E2 to 15 keto 13,14 dihydro prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator activated receptor. Alternative splicing results in multiple transcript variants.