Raf-1(Phospho Ser338) Polyclonal Antibody, 50ul General Lab Use May mediate accelerated ATP-independent bidirectional

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane

In the Goodpasture syndrome

Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton

and chloride channels

and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation

Raf-1(Phospho Ser338) Polyclonal Antibody, 50ul General Lab Use May mediate accelerated ATP-independent bidirectionalThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.