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TRPV5 Polyclonal Antibody, 100ul Buffer Solutions Oncogenic fusions of the 5'

SKU: 65262837663

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DKK108.00 DKK144.00

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TRPV5 Polyclonal Antibody, 100ul Buffer Solutions Oncogenic fusions of the 5'This gene is a member of the transient receptor family and the TrpV subfamily. The calcium selective channel encoded by this gene has 6 transmembrane spanning domains, multiple potential phosphorylation sites, an N linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

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Description

Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias

VEGFB encodes a member of the PDGF (platelet-derived growth factor) /VEGF (vascular endothelial growth factor) family

Interacts with NCOA3 and NCOA6 coactivators| leading to a strong increase of transcription of target genes

has been found to be required for IKK activation by this protein

This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus

TRPV5 Polyclonal Antibody, 100ul Buffer Solutions Oncogenic fusions of the 5'This gene is a member of the transient receptor family and the TrpV subfamily. The calcium selective channel encoded by this gene has 6 transmembrane spanning domains, multiple potential phosphorylation sites, an N linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

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