MRP-L22 Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene are

Mutations in this gene are associated with osteoarthritis in humans

Alternative splicing of this gene results in several transcript variants encoding three different isoforms

may play a role in the mucosal/epithelial immune response and epidermal differentiation

Related pseudogenes have been identified on chromosomes 7 and 14

A Ser310Ala polymorphism has been associated with schizophrenia| and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics

MRP-L22 Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene areMammalian mitochondrial ribosomal proteins are encoded by MRPL22 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.