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HXK II Monoclonal Antibody, 100ul[BT-MCA0760] Enzymes A mutation in this gene

SKU: 63839719210

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SEK135.00 SEK178.00

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HXK II Monoclonal Antibody, 100ul[BT-MCA0760] Enzymes A mutation in this geneHexokinases phosphorylate glucose to produce glucose 6 phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

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Description

A mutation in this gene is associated with ankylosing spondylitis

and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells

Belongs to the AAA ATPase family

suggesting either heavy glycosylation or dimerization

known as the poor metabolizer and extensive metabolizer phenotypes

HXK II Monoclonal Antibody, 100ul[BT-MCA0760] Enzymes A mutation in this geneHexokinases phosphorylate glucose to produce glucose 6 phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

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