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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges Certain single-nucleotide polymorphism haplotypes of

SKU: 63680179133

4.6
PLN97.20 PLN126.20

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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges Certain single-nucleotide polymorphism haplotypes ofThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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Description

Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

and it is found in the mitochondrial intermembrane space in healthy cells

which interacts with histone deacetylase

Two transcript variants encoding different isoforms have been found for CSNK2B

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges Certain single-nucleotide polymorphism haplotypes ofThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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