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Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment a member of the short-chain

SKU: 63472562623

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Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment a member of the short-chainThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

a member of the short-chain dehydrogenase/reductase superfamily

Mutations in this gene can cause early-onset axonal neuropathy

EDNRA encodes the receptor for endothelin-1

The protein encoded by DDR1 (discoidin domain receptor tyrosine kinase 1) belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain

postaxial polydactyly types A1 and B

Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment a member of the short-chainThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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