Flk-1 Polyclonal Antibody, 50ul[BT-AP03272] PCR Series a mutant defective in DNA

a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination

disease:Defects in RAD54B may be a cause of tumor formation

threonine asparginine

Two alternatively spliced transcript variants are expressed by the gene

This gene is up-regulated in various cancers

Flk-1 Polyclonal Antibody, 50ul[BT-AP03272] PCR Series a mutant defective in DNAVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs