PLCB4 Polyclonal Antibody, 100ul Bacterial Expression chromosomal aberrations involving this gene

chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors

and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa

The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex

PRKAR1A can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

PLCB4 Polyclonal Antibody, 100ul Bacterial Expression chromosomal aberrations involving this geneThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene.