AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis Mutations in MT-CO1 have been

Mutations in MT-CO1 have been associated with Leber's hereditary optic neuropathy (LHON)

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis

The protein encoded by this gene is involved in processes including neurite growth and migration

neurotransmitter phenotype

It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis Mutations in MT-CO1 have beenAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and