Caspase-3 mouse Monoclonal Antibody(5H10), 50ul DNA Fragments The product of this gene

The product of this gene is a type II integral membrane protein

Isoform 2 is testis specific

BCLAF1encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins

In addition| the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides| localize to promoters and CpG islands| and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2| an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA

This protein mediates the signal of the transforming growth factor (TGF)-beta| and thus regulates multiple cellular processes| such as cell proliferation| apoptosis| and differentiation

Caspase-3 mouse Monoclonal Antibody(5H10), 50ul DNA Fragments The product of this geneThis gene encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the