NBPF5 Polyclonal Antibody, 50ul Capsule Filter Down-regulation of this gene has

Down-regulation of this gene has been associated with a variety of human epithelial malignancies

This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides

A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing

Binding generally results in the modulation of the activity of the binding partner

immune-mediated inflammatory diseases and feeding regulation

NBPF5 Polyclonal Antibody, 50ul Capsule Filter Down-regulation of this gene hasNBPF5 (neuroblastoma breakpoint family member 5) is a 351 amino acid cytoplasmic protein that is expressed in medulla and brain and belongs to the NBPF family. NBPF5 contains one NBPF domain and is encoded by a gene that maps to human chromosome 1p13. Chromosome 1 spans 260 million base pairs, contains over 3000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease associated genes, including those that are