CAMLG Polyclonal Antibody, 20ul Endonucleases & Exonucleases The GPI-anchor is found on

The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface

Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

It is a glycoprotein that is particularly abundant in kidney

SVOP (SV2 Related Protein) is a Protein Coding gene

CAMLG Polyclonal Antibody, 20ul Endonucleases & Exonucleases The GPI-anchor is found onThe immunosuppressant drug cyclosporin A blocks a calcium dependent signal from the T cell receptor (TCR) that normally leads to T cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This