IκB-alpha Polyclonal Antibody, 100ul[BT-AP10544] Enzyme-Linked Immunosorbent Assay (ELISA) FACT (facilitates chromatin transcription)

FACT (facilitates chromatin transcription)

the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division

which is required for synaptic vesicle docking and fusion

see PSG1 (MIM 176390)

Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6)

IκB-alpha Polyclonal Antibody, 100ul[BT-AP10544] Enzyme-Linked Immunosorbent Assay (ELISA) FACT (facilitates chromatin transcription)This gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell