DMPK Polyclonal Antibody, 100ul Rotator These isoforms show expression that

These isoforms show expression that is spatially and temporally regulated during development

which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers

Activated by intracellular alkalinization

the encoded protein is also required for molybdenum cofactor biosynthesis

Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD)

DMPK Polyclonal Antibody, 100ul Rotator These isoforms show expression thatDystrophia myotonica protein kinase encoded by DMPK is a serine threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta subunit of the L type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5 38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50 5,000 copies causes