SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases nuclear DNA-binding protein regulates transcription

nuclear DNA-binding protein regulates transcription

May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death

DVL2 and/or DVL3)

A number of genes are fusion partners have been characterized

T-cell receptor enhancers and GM-CSF promoters

SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases nuclear DNA-binding protein regulates transcriptionThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.