NFKappaB-p105/p50 Polyclonal Antibody, 20ul[BT-AP05981] In vitro Assessment The inter-alpha-trypsin inhibitors (ITI) are

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis

and confers oncogenic transformation of primary cells

ERAS may be involved in cancer and chemotherapy resistance

Mutations in this gene are also associated with complete androgen insensitivity (CAIS)

and thus mediates immediate-early gene expression in response to cell stimuli

NFKappaB-p105/p50 Polyclonal Antibody, 20ul[BT-AP05981] In vitro Assessment The inter-alpha-trypsin inhibitors (ITI) areNFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines, oxidant free radicals, ultraviolet irradiation, and