UBP34 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges PSPN encodes a secreted ligand

PSPN encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins

and symptomatic epilepsy (PMSE) syndrome

The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD)

and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA

Huntington's disease and temporal lobe epilepsy

UBP34 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges PSPN encodes a secreted ligandCatalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,Recognizes and hydrolyzes the peptide bond at the C terminal Gly of ubiquitin. Involved in the processing of poly ubiquitin precursors as well as that of ubiquinated proteins.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the peptidase C19 family.,tissue specificity: Expressed in brain at low level.,