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SACS Polyclonal Antibody, 100ul Lentiviral Packaging Multiple alternatively spliced variants encoding

SKU: 61657728308

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SACS Polyclonal Antibody, 100ul Lentiviral Packaging Multiple alternatively spliced variants encodingThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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Description

Multiple alternatively spliced variants encoding different isoforms have been identified

and in regulating normal cell survival and proliferation

Binding occurs as a ternary complex of methionyl-tRNA

The tropomyosin alpha-1 chain is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle

Multiple transcript variants encoding different isoforms have been found for SPTBN1

SACS Polyclonal Antibody, 100ul Lentiviral Packaging Multiple alternatively spliced variants encodingThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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