Rho A Polyclonal Antibody, 100ul Nucleic Acid Extraction A duplication of LMNB1 is

A duplication of LMNB1 is associated with autosomal dominant adult-onset leukodystrophy (ADLD)

MIM 606462) by ESPL1| or separase| which initiates the final separation of sister chromatids (Sun et al

The expression of this gene may be regulated by peroxisome proliferator-activated receptor gamma

spleen and fetal tissues

and therefore is about 800 aa longer than the other MAGE proteins

Rho A Polyclonal Antibody, 100ul Nucleic Acid Extraction A duplication of LMNB1 isRHOA encodes a member of the Rho family of small GTPases, which cycle between inactive GDP bound and active GTP bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.